CMI researchers from Colorado School of Mines and Idaho National Laboratory conducted the research for this highlight.
Experiments with model nitrifier Nitrosomonas europaea had indicated inhibition by 50 ppm yttrium; we examined the whole transcriptome response.
- 282 differentially expressed genes compared to the no Y control were identified.
- Up-regulated genes included lipopolysaccharide synthesis proteins (implicated in antibiotic resistance) and down-regulated genes included metalloproteins.
Significance and Impact
Identification of impacted proteins provides insight into mechanisms for observed inhibition as well as potential latent effects on ecosystem functions.
Hub Target Addressed
Supporting environmentally sustainable critical material processing.
- Lipopolysaccharide biosynthesis
- Amino acid biosynthesis
- ABC Transporters
- Ammonium oxidation
- Many metalloproteins
- Unknown functions