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Supramolecular assemblies of alkane functionalized polyethylene glycol copolymers for drug delivery

TitleSupramolecular assemblies of alkane functionalized polyethylene glycol copolymers for drug delivery
Publication TypeJournal Article
Year of Publication2017
AuthorsZhu, LD, Bratlie, KM
Journal Engineering C-Materials for Biological Applications
Volume81
Pagination432-442
Date Published12
Type of ArticleArticle
ISBN Number0928-4931
Accession NumberWOS:000410253800053
Keywordscytotoxicity, design, gene delivery, in-vitro, Macrophage phenotype, Materials Science, micelles, micellization, nanoparticles, poly(dmaema-co-ppgma), release
Abstract

capacity of the drug in the various micelles did not correlate with the internalization of the particles into the cells. Factorial analysis was used to develop predictive equations for drug loading, drug release kinetics, and cell internalization. These models were validated with newly synthesized compounds.

DOI10.1016/j.msec.2017.08.046
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