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LEGO (R) Bricks as Building Blocks for Centimeter-Scale Biological Environments: The Case of Plants

TitleLEGO (R) Bricks as Building Blocks for Centimeter-Scale Biological Environments: The Case of Plants
Publication TypeJournal Article
Year of Publication2014
AuthorsLind, KR, Sizmur, T, Benomar, S, Miller, A, Cademartiri, L
JournalPlos One
Volume9
Paginatione100867
Date Published06
Type of ArticleArticle
ISBN Number1932-6203
Accession NumberWOS:000338709500092
Keywords3d cell-culture, arabidopsis-thaliana, growth, microfluidic chip, root-system architecture, soil, tissue
Abstract

LEGO bricks are commercially available interlocking pieces of plastic that are conventionally used as toys. We describe their use to build engineered environments for cm-scale biological systems, in particular plant roots. Specifically, we take advantage of the unique modularity of these building blocks to create inexpensive, transparent, reconfigurable, and highly scalable environments for plant growth in which structural obstacles and chemical gradients can be precisely engineered to mimic soil.

DOI10.1371/journal.pone.0100867
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