Conversions of Cyclic Amines to Nylon Precursor Lactams Using Bulk Gold and Fumed Silica Catalysts

TitleConversions of Cyclic Amines to Nylon Precursor Lactams Using Bulk Gold and Fumed Silica Catalysts
Publication TypeJournal Article
Year of Publication2011
AuthorsKlobukowski ER, Mueller ML, Angelici RJ, Woo LK
Journal TitleACS Catalysis
Volume1
Pages703-708
Date Published07
ISBN Number2155-5435
Accession NumberWOS:000292479400005
Abstract

Bulk gold powder (similar to 50 mu m) and alumina-supported gold catalyzed the oxidative dehydrogedation of 5-, 6-, and 7-membered cyclic amines to amidines. These amidines were hydrolyzed upon treatment with Aerosil 200 (fumed silica gel) and water, producing lactams in 42-73% yields and amines in 36-63% yields. The gold and Aerosil 200 catalysts could also be combined in a one-Pot reaction to catalyze the conversion of cyclic amines to lactams in yields up to 51%.

DOI10.1021/cs200120c