Mass Spectrometric Imaging

We are developing mass spectrometric imaging technique to analyze plant metabolites in single cell level. With this new technique, we can reveal unprecedented details of plant metabolism.

We are using top-notch instrumentation for this project, matrix-assisted laser desorption ionization (MALDI)-linear ion trap-orbitrap mass spectrometer. By reducing the laser beam size down to 10um size, we can probe molecules present in very narrow area, and acquire high-resolution mass spectra for over thousands of x and y positions.

Knowledge on instrumental analysis is recommended but not required. Students will learn about mass spectrometry and bioanalytical chemistry technique that may be useful in their career.

Program mentor: Young-Jin Lee, associate scientist, Ames Laboratory

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