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Neuroregenerative and Neurorepair Strategies

This highly interdisciplinary project seeks to develop approaches to facilitate repair and regeneration of the damaged nervous system. We will use a combination of biomaterials in the form of polymer conduits and/or scaffolds, adult stem cells seeded on the biomaterials, and use of physical, chemical, biological and/or electrical cues to orient cell growth, control stem cell differentiation and facilitate neuroregeneration using in vitro models. Interns will have the opportunity to observe and learn the following techniques: general laboratory procedures, data collection and analysis, mammalian cell culture, immunocytochemical procedures, fluorescence microscopy, image analysis, and tissue engineering strategies.

Mentor: Donald Sakaguchi, Professor, Genetics, Development and Cell Biology, Iowa State University