Conversions of Cyclic Amines to Nylon Precursor Lactams Using Bulk Gold and Fumed Silica Catalysts
|Title||Conversions of Cyclic Amines to Nylon Precursor Lactams Using Bulk Gold and Fumed Silica Catalysts|
|Publication Type||Journal Article|
|Year of Publication||2011|
|Authors||Klobukowski ER, Mueller ML, Angelici RJ, Woo LK|
|Journal Title||ACS Catalysis|
Bulk gold powder (similar to 50 mu m) and alumina-supported gold catalyzed the oxidative dehydrogedation of 5-, 6-, and 7-membered cyclic amines to amidines. These amidines were hydrolyzed upon treatment with Aerosil 200 (fumed silica gel) and water, producing lactams in 42-73% yields and amines in 36-63% yields. The gold and Aerosil 200 catalysts could also be combined in a one-Pot reaction to catalyze the conversion of cyclic amines to lactams in yields up to 51%.