Cell-induced intracellular controlled release of membrane impermeable cysteine from a mesoporous silica nanoparticle-based drug delivery system

TitleCell-induced intracellular controlled release of membrane impermeable cysteine from a mesoporous silica nanoparticle-based drug delivery system
Publication TypeJournal Article
Year of Publication2009
AuthorsMortera R, Vivero-Escoto J, Slowing II, Garrone E, Onida B, Lin VSY
Journal TitleChemical Communications
Pages3219-3221
ISBN Number1359-7345
Accession NumberISI:000266555300021
Keywordscancer-cells, cardiovascular-disease, culture, functionalization, glutathione, n-acetylcysteine, oxidative stress, proteins
Abstract

A mesoporous silica nanoparticle-based intracellular cysteine delivery system that could be induced and regulated by cell-produced natural antioxidants was synthesized.

URL<Go to ISI>://000266555300021
DOI10.1039/B900559e