Dr. Ning Fang

Ames Laboratory Associate and Assistant Professor, Iowa State University
Address
2101C Hach Hall
Iowa State University
Ames, IA 50011
Phone 515-294-3206
Email nfang@iastate.edu

Research Interests

Far-field optical imaging methods are essential for precise visualization of the dynamics of biomolecules and nanoparticles because they require no contact and make minimal intrusion to the sample. The research in the Fang Laboratory is aimed to open up new frontiers in chemical and biological discovery through the development and use of a novel optical imaging platform, which provides sub-diffraction-limited spatial resolution, high angular resolution, excellent detectability, and nanometer localization precision for single molecules and nanoparticles in live biological samples and microfluidic devices.


        Project Affiliations:

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(Chronologically most recent on top)Education

  • 2006  Ph.D., the University of British Columbia, Canada
  • 1998  B.S. from Xiamen University, China

(Chronologically most recent on top)Professional Appointments

  • 2008 - present  Assistant Professor, Department of Chemistry, Iowa State University
  • 2006 to 2008    Postdoctoral Associate at Iowa State University with Prof. Edward S. Yeung

(Chronologically most recent on top)Publications with the Ames Laboratory

2010
Wang G F; Sun W; Luo Y; Fang N . 2010. Resolving Rotational Motions of Nano-objects in Engineered Environments and Live Cells with Gold Nanorods and Differential Interference Contrast Microscopy. Journal of the American Chemical Society. 132:16417-16422. abstract
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Sun W; Marchuk K; Wang G F; Fang N . 2010. Autocalibrated Scanning-Angle Prism-Type Total Internal Reflection Fluorescence Microscopy for Nanometer-Precision Axial Position Determination. Analytical Chemistry. 82:2441-2447. abstract
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Liu C; Luo Y; Maxwell E J; Fang N; Chen D D Y . 2010. Reverse of Mixing Process with a Two-Dimensional Electro-Fluid-Dynamic Device. Analytical Chemistry. 82:2182-2185. abstract
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Wang G F; Stender A S; Sun W; Fang N . 2010. Optical imaging of non-fluorescent nanoparticle probes in live cells. Analyst. 135:215-221. abstract
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2009
Sun W; Wang G F; Fang N; Yeung E S . 2009. Wavelength-Dependent Differential Interference Contrast Microscopy: Selectively Imaging Nanoparticle Probes in Live Cells. Analytical Chemistry. 81:9203-9208. abstract
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Li J W; Xie W J; Fang N; Yeung E S . 2009. Single-molecule immunosorbent assay as a tool for human immunodeficiency virus-1 antigen detection. Analytical and Bioanalytical Chemistry. 394:489-497. abstract
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2008
Sun W; Fang N; Trewyn B G; Tsunoda M; Slowing I I; Lin V S Y; Yeung E S . 2008. Endocytosis of a single mesoporous silica nanoparticle into a human lung cancer cell observed by differential interference contrast microscopy. Analytical and Bioanalytical Chemistry. 391:2119-2125. abstract
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Zhang H; Brokman S M; Fang N; Pohl N L; Yeung E S . 2008. Linkage position and residue identification of disaccharides by tandem mass spectrometry and linear discriminant analysis. Rapid Communications in Mass Spectrometry. 22:1579-1586. abstract
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2007
Fang N; Li J W; Yeung E S . 2007. Quantitative analysis of systematic errors originated from wall adsorption and sample plug lengths in affinity capillary electrophoresis using two-dimensional simulation. Analytical Chemistry. 79:5343-5350. abstract
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Fang N; Zhang H; Li J W; Li H W; Yeung E S . 2007. Mobility-based wall adsorption isotherms for comparing capillary electrophoresis with single-molecule observations. Analytical Chemistry. 79:6047-6054. abstract
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