Dr. Igor I. Slowing

Associate Scientist
Address
2756 Gilman Hall
Iowa State University
Ames, IA 50011
Phone 515-294-1959
Email islowing@iastate.edu

Research Interests

Synthesis and development of mesoporous nanoparticles for catalysis, energy transduction, and in situ refinery of biocommodities.  Coupling biocatalysis with thermo and photocatalysis.Studies of interactions between nanoparticles and cells.


        Project Affiliations:
        Nanorefinery

(Chronologically most recent on top)Education

  • 2003-2008 Ph.D. Iowa State University
  • 1988-1995 Licenciate in Chemistry, San Carlos University, Guatemala

(Chronologically most recent on top)Professional Appointments

  • 2009-present Staff Scientist, Ames Laboratory
  • 2005-2008 Research assistant, Iowa State University
  • 2000-2003 Lecturer, Del Valle University, Guatemala
  • 1996-2003 Lecturer, San Carlos University, Guatemala

(Chronologically most recent on top)Honors & Awards

  • Inventor Incentive Award, Ames Laboratory, 2009
  • Cotton-Uphaus Award for early achievements in research, Iowa State University, 2006

(Chronologically most recent on top)Publications with the Ames Laboratory

2010
Vivero-Escoto J L; Slowing I I; Lin V S Y . 2010. Tuning the cellular uptake and cytotoxicity properties of oligonucleotide intercalator-functionalized mesoporous silica nanoparticles with human cervical cancer cells HeLa. Biomaterials. 31:1325-1333. abstract
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2009
Vivero-Escoto J L; Slowing I I; Wu C W; Lin V S Y . 2009. Photoinduced Intracellular Controlled Release Drug Delivery in Human Cells by Gold-Capped Mesoporous Silica Nanosphere. Journal of the American Chemical Society. 131:3462-+. abstract
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Zhao Y N; Trewyn B G; Slowing I I; Lin V S Y . 2009. Mesoporous Silica Nanoparticle-Based Double Drug Delivery System for Glucose-Responsive Controlled Release of Insulin and Cyclic AMP. Journal of the American Chemical Society. 131:8398-+. abstract
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Slowing I I; Wu C W; Vivero-Escoto J L; Lin V S Y . 2009. Mesoporous Silica Nanoparticles for Reducing Hemolytic Activity Towards Mammalian Red Blood Cells. Small. 5:57-62. abstract
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Mortera R; Vivero-Escoto J; Slowing I I; Garrone E; Onida B; Lin V S Y . 2009. Cell-induced intracellular controlled release of membrane impermeable cysteine from a mesoporous silica nanoparticle-based drug delivery system. Chemical Communications. :3219-3221. abstract
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2008
Kim T W; Chung P W; Slowing I I; Tsunoda M; Yeung E S; Lin V S Y . 2008. Structurally Ordered Mesoporous Carbon Nanoparticles as Transmembrane Delivery Vehicle in Human Cancer Cells. Nano Letters. 8:3724-3727. abstract
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Slowing I I; Vivero-Escoto J L; Wu C W; Lin V S Y . 2008. Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. Advanced Drug Delivery Reviews. 60:1278-1288. abstract
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Sun W; Fang N; Trewyn B G; Tsunoda M; Slowing I I; Lin V S Y; Yeung E S . 2008. Endocytosis of a single mesoporous silica nanoparticle into a human lung cancer cell observed by differential interference contrast microscopy. Analytical and Bioanalytical Chemistry. 391:2119-2125. abstract
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2007
Trewyn B G; Slowing I I; Giri S; Chen H T; Lin V S Y . 2007. Synthesis and functionalization of a mesoporous silica nanoparticle based on the sol-gel process and applications in controlled release. Accounts of Chemical Research. 40:846-853. abstract
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Slowing I I; Trewyn B G; Giri S; Lin V S Y . 2007. Mesoporous silica nanoparticles for drug delivery and biosensing applications. Advanced Functional Materials. 17:1225-1236. abstract
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